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Nucleosil – standard silica phases for HPLC


Silica- The standard in HPLC


NUCLEOSIL® ion exchangers
These phases have been especially developed for HPLC.
Contrary to adsorptions or reversed phase chromatography
with ion exchange chromatography there are three variable
parameters for the mobile phase, which can influence the
-the type of buffer,
-the ionic strength and
-the pH value.

NUCLEOSIL® is a family of totally porous spherical silicas. They feature a very pure and uniform SiO2 structure and have gained wide acceptance as outstanding chromatographic packing for very different fields of modern chromatography.

Due to its particle sizes NUCLEOSIL finds application in analytical as well as in preparative columnsIt allows

  • High bed stability due to spherical particles
  • High efficiency due to narrow particle size distribution
  • High separation performance due to optimized binding techniques
  • High chemical and mechanical stability
  • High load capacity and recovery rates
  • High reproducibility from lot to lot

Nucleosil Brochure  

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